In 'Genentech', Sally Smith Hughes unveils the captivating story of the biotechnology revolution sparked by one extraordinary company. This in-depth account charts the rise of Genentech from a daring startup to a leader in medical science, reshaping the landscape of healthcare. Hughes intricately weaves personal narratives with scientific breakthroughs, exploring the lives and ambitions of the pioneers behind the company. Readers will be intrigued by the ethical dilemmas and fierce rivalries that emerged in the quest for innovation. Discover how Genentech’s journey not only transformed medicine but also ignited debates about the future of biotech.
By Sally Smith Hughes
Published: 2013
"In the intricate dance of science and ambition, Genentech emerged as a beacon of innovation, reminding us that the pursuit of knowledge often leads us to unexpected horizons."
In the fall of 1980, Genentech, Inc., a little-known California genetic engineering company, became the overnight darling of Wall Street, raising over $38 million in its initial public stock offering. Lacking marketed products or substantial profit, the firm nonetheless saw its share price escalate from $35 to $89 in the first few minutes of trading, at that point the largest gain in stock market history. Coming at a time of economic recession and declining technological competitiveness in the United States, the event provoked banner headlines and ignited a period of speculative frenzy over biotechnology as a revolutionary means for creating new and better kinds of pharmaceuticals, untold profit, and a possible solution to national economic malaise. Drawing from an unparalleled collection of interviews with early biotech players, Sally Smith Hughes offers the first book-length history of this pioneering company, depicting Genentech’s improbable creation, precarious youth, and ascent to immense prosperity. Hughes provides intimate portraits of the people significant to Genentech’s science and business, including cofounders Herbert Boyer and Robert Swanson, and in doing so sheds new light on how personality affects the growth of science. By placing Genentech’s founders, followers, opponents, victims, and beneficiaries in context, Hughes also demonstrates how science interacts with commercial and legal interests and university research, and with government regulation, venture capital, and commercial profits. Integrating the scientific, the corporate, the contextual, and the personal, Genentech tells the story of biotechnology as it is not often told, as a risky and improbable entrepreneurial venture that had to overcome a number of powerful forces working against it.
Showing 8 of 20 similar books
Alexis Ohanian is an American entrepreneur, investor, and co-founder of Reddit, one of the world’s most popular social news and discussion platforms. Ohanian is also a prominent advocate for open internet and net neutrality, and he has invested in numerous startups through his venture capital firm, Initialized Capital. In addition to his work in tech, Ohanian is involved in philanthropy, supporting causes related to women’s rights, education, and social justice. He is married to tennis star Serena Williams, and together they advocate for gender equality and inclusive leadership. Ohanian’s influence in the tech world and his commitment to social impact have made him a respected figure in both business and activism.
Andrew Chen is a venture capitalist, entrepreneur, and thought leader in growth marketing, currently serving as a general partner at Andreessen Horowitz. Chen is known for his expertise in network effects, viral growth strategies, and marketplace dynamics, making him a sought-after advisor for startups looking to scale. Prior to joining Andreessen Horowitz, he worked in leadership roles at Uber, helping to grow the ride-sharing platform’s user base and develop key growth strategies. Chen is also a prolific writer, sharing his insights on growth, technology, and startups through his popular blog and newsletter, which has attracted a loyal following in the tech community. His work has helped shape how many startups approach user acquisition, retention, and product-market fit. As a venture capitalist, Chen focuses on early-stage companies in the consumer internet, SaaS, and marketplace sectors, and he has been involved in funding and advising several successful startups. His insights on technology and growth continue to influence both founders and investors alike.
Alfred Lin is a venture capitalist and partner at Sequoia Capital, where he focuses on investments in consumer internet, enterprise, and mobile companies. Lin is known for his early investments in companies like Airbnb and DoorDash, helping them grow into major global brands. Before joining Sequoia, Lin was an executive at Zappos, where he worked closely with CEO Tony Hsieh to develop the company’s innovative culture and customer service model. Lin’s expertise in scaling businesses and his strategic vision have made him one of the most respected venture capitalists in Silicon Valley.
Adam Grant is a renowned organizational psychologist and bestselling author, celebrated for his influential work on motivation and workplace dynamics. He is a professor at the Wharton School of the University of Pennsylvania, where he has been the youngest tenured professor and earned numerous teaching awards. Grant's books, including "Give and Take," "Originals," and "Think Again," have been translated into multiple languages and have topped bestseller lists worldwide. His research and insights are frequently featured in major media outlets, and he hosts the popular podcast "WorkLife." Through his writing and speaking, Grant has profoundly impacted the fields of psychology, business, and education.
“In the intricate dance of science and ambition, Genentech emerged as a beacon of innovation, reminding us that the pursuit of knowledge often leads us to unexpected horizons.”
Genentech
By Sally Smith Hughes
Discover a world of knowledge through our extensive collection of book summaries.
Sally Smith Hughes is an accomplished author and historian known for her insightful exploration of the intersections between science, history, and culture. Her notable works include 'The Science of History', which examines the role of scientific inquiry in historical narratives, and 'Mind and Matter: A History of Ideas', celebrated for its engaging prose and thorough research. Hughes' writing style is characterized by a clear and accessible approach, making complex subjects understandable to a broad audience. With a background in history and a passion for storytelling, she continues to contribute significantly to contemporary literature and historical scholarship.
Key information about the book.
Support local bookstores: BookShop gives a portion of each sale to independent bookshops!
In "Den of Thieves," journalist James B. Stewart pulls back the curtain on the high-stakes world of corporate America during the 1980s. This riveting narrative chronicles the lives of power brokers and insider traders who bent the rules to accumulate unimaginable wealth. As greed intertwines with ambition, a thrilling tale of deception unfolds, leading to dramatic investigations and shocking convictions. Stewart masterfully blends real-life drama with insights into the financial markets, leaving readers on the edge of their seats. Dive into the labyrinth of moral ambiguity and see how far the quest for success can lead one astray!
In "Business Adventures," renowned author John Brooks takes readers on a captivating journey through twelve compelling tales of corporate triumphs and failures. These real-world stories illuminate the timeless lessons of business, from the stock market collapse of 1962 to the explosive rise of Xerox. Each narrative is densely packed with intrigue, showcasing the human elements that drive decisions and shape outcomes in the corporate world. With sharp insights and humor, Brooks reveals the unpredictable nature of business that still resonates today. Prepare to be fascinated by the compelling drama that unfolds in the boardrooms and backrooms where fortunes are made and lost.
In "What's Your Problem?", Thomas Wedell-Wedellsborg challenges traditional approaches to problem-solving by urging readers to rethink and reframe their issues. Through insightful anecdotes and practical frameworks, he demonstrates how the way we define a problem can drastically alter the solution. The book reveals that many great ideas are born from asking better questions, transforming the complexities of challenges into actionable insights. Wedell-Wedellsborg invites us to embrace a mindset shift that fosters creativity and innovation. Are you ready to unlock the true potential of your problems?
In 'Can't Hurt Me', David Goggins shares his extraordinary journey from a troubled childhood to becoming a Navy SEAL and ultra-endurance athlete. Goggins confronts the limits of the human spirit, challenging readers to push beyond their perceived capabilities. Through harrowing stories of perseverance, he reveals the transformative power of accountability and mental toughness. This memoir is not just a tale of resilience, but a call to embrace discomfort as a pathway to greatness. Are you ready to redefine your limits and discover what you’re truly capable of?
'Billion Dollar Whale' uncovers the extraordinary true story of the massive financial fraud behind 1MDB, one of the world's largest embezzlement scandals. Follow the rise of Jho Low, a young Malaysian financier, as he dazzles global elites with opulence while masterminding a scheme that siphons billions from a sovereign wealth fund. With thrilling twists and high-stakes intrigue, the book reveals the complicity of international banks, Hollywood moguls, and political figures in the scandal. Just how did Low manage to pull off this elaborate deception? Dive into this gripping narrative to uncover the secrets and audacious ambitions that changed the landscape of finance and politics.
In 'Financial Shenanigans,' the authors unveil the art of identifying accounting tricks that can mislead investors and stakeholders. They provide detailed insights into the deceptive practices that companies often employ to present a misleading financial picture. Each chapter reveals real-world examples, equipping readers with tools to spot financial fraud before it’s too late. As financial reports become increasingly complex, this guide shines a light on the dark corners of corporate accounting. Are you prepared to uncover the hidden truths lurking within financial statements?
In 'Inevitable Revolutions', Walter LaFeber delves into the history of U.S. involvement in Central America, revealing the complex interplay between ideologies and national interests. With eloquent storytelling, LaFeber highlights the economic and political forces that led to revolutions, casting a revealing light on America's role as both a supporter and suppressor of democracy. The book challenges readers to reconsider the narrative of American exceptionalism, raising questions about accountability and the consequences of intervention. Through case studies of specific nations, LaFeber illustrates the paradox of U.S. foreign policy—intentions versus outcomes. This thought-provoking work leaves readers pondering the true cost of 'freedom' as seen through the lens of American influence.
In 'Anything You Want,' Derek Sivers shares his unconventional journey from bartender to the founder of CD Baby, a platform that revolutionized music distribution. With his signature wit and wisdom, Sivers delves into the lessons he's learned about entrepreneurship, passion, and authenticity. The book challenges conventional business wisdom and emphasizes the importance of personal values in shaping success. Through engaging anecdotes, Sivers inspires readers to pursue what truly matters to them and to define success on their own terms. Are you ready to rethink your approach to life and business?