In 'Genentech', Sally Smith Hughes unveils the captivating story of the biotechnology revolution sparked by one extraordinary company. This in-depth account charts the rise of Genentech from a daring startup to a leader in medical science, reshaping the landscape of healthcare. Hughes intricately weaves personal narratives with scientific breakthroughs, exploring the lives and ambitions of the pioneers behind the company. Readers will be intrigued by the ethical dilemmas and fierce rivalries that emerged in the quest for innovation. Discover how Genentech’s journey not only transformed medicine but also ignited debates about the future of biotech.
By Sally Smith Hughes
Published: 2013
"In the intricate dance of science and ambition, Genentech emerged as a beacon of innovation, reminding us that the pursuit of knowledge often leads us to unexpected horizons."
In the fall of 1980, Genentech, Inc., a little-known California genetic engineering company, became the overnight darling of Wall Street, raising over $38 million in its initial public stock offering. Lacking marketed products or substantial profit, the firm nonetheless saw its share price escalate from $35 to $89 in the first few minutes of trading, at that point the largest gain in stock market history. Coming at a time of economic recession and declining technological competitiveness in the United States, the event provoked banner headlines and ignited a period of speculative frenzy over biotechnology as a revolutionary means for creating new and better kinds of pharmaceuticals, untold profit, and a possible solution to national economic malaise. Drawing from an unparalleled collection of interviews with early biotech players, Sally Smith Hughes offers the first book-length history of this pioneering company, depicting Genentech’s improbable creation, precarious youth, and ascent to immense prosperity. Hughes provides intimate portraits of the people significant to Genentech’s science and business, including cofounders Herbert Boyer and Robert Swanson, and in doing so sheds new light on how personality affects the growth of science. By placing Genentech’s founders, followers, opponents, victims, and beneficiaries in context, Hughes also demonstrates how science interacts with commercial and legal interests and university research, and with government regulation, venture capital, and commercial profits. Integrating the scientific, the corporate, the contextual, and the personal, Genentech tells the story of biotechnology as it is not often told, as a risky and improbable entrepreneurial venture that had to overcome a number of powerful forces working against it.
Showing 8 of 25 similar books
Naval Ravikant is an entrepreneur, angel investor, and philosopher, best known as the co-founder of AngelList, a platform that connects startups with investors. Ravikant is a prolific thinker and writer on topics such as startups, investing, and personal well-being, sharing his wisdom through essays, podcasts, and social media. He has invested in over 100 companies, including Uber, Twitter, and Yammer, making him one of Silicon Valley’s most successful angel investors. Ravikant is also known for his philosophical musings on wealth, happiness, and the meaning of life, which have garnered him a large and dedicated following.
Alexis Ohanian is an American entrepreneur, investor, and co-founder of Reddit, one of the world’s most popular social news and discussion platforms. Ohanian is also a prominent advocate for open internet and net neutrality, and he has invested in numerous startups through his venture capital firm, Initialized Capital. In addition to his work in tech, Ohanian is involved in philanthropy, supporting causes related to women’s rights, education, and social justice. He is married to tennis star Serena Williams, and together they advocate for gender equality and inclusive leadership. Ohanian’s influence in the tech world and his commitment to social impact have made him a respected figure in both business and activism.
Ana Lorena Fabrega is an innovative educator and author passionate about reimagining education. Known as “Ms. Fab,” she is the Chief Evangelist at Synthesis, an education startup inspired by the problem-solving and collaboration model used at SpaceX. She advocates for alternative learning methods, encouraging curiosity and creativity in students. Ana's work emphasizes the importance of engaging young learners in real-world challenges and critical thinking. She also shares insights on education reform through her popular newsletter, Fab Fridays.
Gary Vaynerchuk, also known as GaryVee, is a serial entrepreneur, investor, and social media personality. He initially gained prominence through his family’s wine business, turning it into a digital juggernaut with his online content and wine reviews. Gary is now the CEO of VaynerMedia, a full-service digital agency, and has authored multiple bestsellers, including Crush It! and Jab, Jab, Jab, Right Hook. He is known for his blunt, motivational style and advice on business, marketing, and personal branding. Gary continues to inspire millions with his focus on hustle, entrepreneurship, and leveraging digital platforms for success.
Bill Gurley is a prominent venture capitalist and general partner at Benchmark, a Silicon Valley venture capital firm. He is best known for his early investments in groundbreaking companies such as Uber, Zillow, and Grubhub, significantly shaping the tech industry's landscape. Gurley's insights into technology and business have been widely disseminated through his influential blog, "Above the Crowd," where he discusses market trends and investment strategies. His thought leadership extends beyond finance, offering valuable perspectives on innovation and entrepreneurship. Bill Gurley's contributions have earned him recognition as one of the most influential figures in venture capital today.
Kevin Rose is a notable entrepreneur and technology investor, best known for founding Digg, a pioneering social news website that significantly influenced online content sharing. Although not primarily recognized for literary contributions, Rose has impacted digital media and online culture, which are recurring themes in contemporary literature on technology. His insights and experiences have been featured in various tech journals and books, enriching discussions on innovation and digital entrepreneurship. Rose also co-hosted the popular podcast "The Random Show" with Tim Ferriss, where he shares his thoughts on technology, health, and productivity. Through his ventures and public speaking, Rose continues to inspire narratives around the digital revolution and startup culture.
Aaron Levie is the co-founder and CEO of Box, a cloud content management platform that revolutionized how businesses manage and collaborate on content. He launched Box in 2005 while still a college student, and the company rapidly grew into a leader in the cloud storage industry. Levie is known for his innovative, forward-thinking approach to enterprise software and for pushing the boundaries of digital transformation. Under his leadership, Box went public in 2015 and continues to evolve with new technologies and partnerships. He is a strong advocate for cloud-first business strategies and frequently shares his insights on the future of work and the digital workplace. Levie is also a prolific speaker and writer, often discussing technology's role in the modern economy. His energetic and witty personality has made him a popular figure in Silicon Valley and beyond.
Andrew Chen is a venture capitalist, entrepreneur, and thought leader in growth marketing, currently serving as a general partner at Andreessen Horowitz. Chen is known for his expertise in network effects, viral growth strategies, and marketplace dynamics, making him a sought-after advisor for startups looking to scale. Prior to joining Andreessen Horowitz, he worked in leadership roles at Uber, helping to grow the ride-sharing platform’s user base and develop key growth strategies. Chen is also a prolific writer, sharing his insights on growth, technology, and startups through his popular blog and newsletter, which has attracted a loyal following in the tech community. His work has helped shape how many startups approach user acquisition, retention, and product-market fit. As a venture capitalist, Chen focuses on early-stage companies in the consumer internet, SaaS, and marketplace sectors, and he has been involved in funding and advising several successful startups. His insights on technology and growth continue to influence both founders and investors alike.
Showing 8 of 17 related collections
“In the intricate dance of science and ambition, Genentech emerged as a beacon of innovation, reminding us that the pursuit of knowledge often leads us to unexpected horizons.”
Genentech
By Sally Smith Hughes
Discover a world of knowledge through our extensive collection of book summaries.
Sally Smith Hughes is an accomplished author and historian known for her insightful exploration of the intersections between science, history, and culture. Her notable works include 'The Science of History', which examines the role of scientific inquiry in historical narratives, and 'Mind and Matter: A History of Ideas', celebrated for its engaging prose and thorough research. Hughes' writing style is characterized by a clear and accessible approach, making complex subjects understandable to a broad audience. With a background in history and a passion for storytelling, she continues to contribute significantly to contemporary literature and historical scholarship.
Key information about the book.
Support local bookstores: BookShop gives a portion of each sale to independent bookshops!
'Billion Dollar Whale' uncovers the extraordinary true story of the massive financial fraud behind 1MDB, one of the world's largest embezzlement scandals. Follow the rise of Jho Low, a young Malaysian financier, as he dazzles global elites with opulence while masterminding a scheme that siphons billions from a sovereign wealth fund. With thrilling twists and high-stakes intrigue, the book reveals the complicity of international banks, Hollywood moguls, and political figures in the scandal. Just how did Low manage to pull off this elaborate deception? Dive into this gripping narrative to uncover the secrets and audacious ambitions that changed the landscape of finance and politics.
In 'The Code Breaker', Walter Isaacson delves into the captivating world of CRISPR gene-editing technology, following the brilliant mind of Jennifer Doudna. This gripping narrative explores the ethical dilemmas and scientific breakthroughs that come with harnessing the power to edit life itself. As researchers grapple with the implications of their discoveries, readers are invited into a fast-paced journey that intertwines science, ambition, and morality. With vivid stories of personal triumphs and challenges, Isaacson raises profound questions about the future of humanity. Will unlocking the secrets of our DNA lead to a utopia or unforeseen consequences?
In 'Disrupted', Dan Lyons takes readers on a wild ride through the chaotic, often comedic landscape of the tech startup world. After being laid off from a traditional job, he finds himself in a young, frenetic company where age and experience clash with the reckless enthusiasm of millennials. Through his sharp wit, Lyons explores the absurdities of corporate culture and the relentless pace of change in the tech industry. But beyond the humor lies a poignant critique of modern work life and the true cost of disruption. As he navigates this new reality, Lyons raises questions about relevance, identity, and the future of work that will leave readers pondering long after the last page.
In 'Nonviolent Communication,' Marshall B. Rosenberg unveils a transformative approach to communication that fosters empathy and connection. He illustrates how breaking down barriers in dialogue can lead to understanding and compassion, rather than conflict. This book guides readers to express their needs authentically and listen deeply to others, cultivating healthier relationships. With real-life examples and practical strategies, Rosenberg's teachings empower individuals to navigate challenging conversations with grace. Discover the power of words to heal and unite in this enlightening exploration of human connection.
In 'Innovation and Entrepreneurship', Peter F. Drucker unveils the secrets of driving economic growth through innovative practices. He emphasizes that innovation is not just the privilege of inventors but a systematic discipline that can be taught and learned. Drucker defines the entrepreneur's role as an agent of change, highlighting how they harness opportunities to create value. Through practical insights and real-world examples, he challenges traditional notions of business and presents a roadmap for successful entrepreneurship. This book is essential for anyone eager to understand the dynamic interplay between innovation and the market!
In "The Second Rule of Ten," the enigmatic detective Tenzing Norbu grapples with a perplexing case that intertwines spirituality and crime. As he delves deeper into the investigation, he uncovers secrets that challenge his understanding of good and evil. Torn between his duty and his own inner turmoil, Tenzing must navigate a world of deception and enlightenment. With each twist and turn, the lines between right and wrong blur, compelling readers to ponder the true nature of justice. This captivating tale invites you to explore the profound mysteries that lie beneath the surface of human experience.
In 'That's What She Said', Joanne Lipman presents a compelling exploration of gender dynamics in the workplace and beyond. Through vivid anecdotes and insightful analysis, she unveils the subtle, often overlooked biases that women face every day. Lipman not only highlights the systemic issues but also offers practical strategies for men and women alike to foster change. This thought-provoking book inspires readers to rethink the narrative around gender and encourages them to take action. Will you join the conversation and challenge the status quo?
In 'Christine', Stephen King unveils the chilling tale of a 1958 Plymouth Fury that possesses a life of its own. As the car's new owner, a troubled teenager named Arnie becomes increasingly obsessed, he transforms from an awkward outcast into a confident and reckless young man. But as Christine's malevolent spirit takes over, Arnie's relationships and sanity begin to unravel, leading to deadly consequences. The story weaves themes of obsession, evil, and the clash between humanity and the machine. Will anyone be able to save Arnie from the grasp of his possessed car before it's too late?